827519
9780195068177
This volume provides an authoritative, up-to-date account of the impact of molecular genetics on our understanding of genetic diseases prevalent among Jews. The extent of genetic variability among different Jewish communities is discussed in detail. After an introductory chapter on major demographic trends of world Jewry, the first part examines ethnohistorical relationships between different Jewish groups in light of nuclear and mictochondrial DNA polymorphisms. The next and largest section of the book reviews the most recent research on some 20 Mendelian disorders (among Ashkenz, Sephardi and Oriental Jews) and the implications of the astonishing molecular heterogeneity revealed in some of them. Advances in genetic aspects of common multifactorial diseases are covered in concluding chapters. This encyclopedic work derives from a conference held in Israel in June 1990. It will be of interest to physicians, genetic counsellors and researchers in medical, molecular, and population genetics.Bonne-Tamir, Batsheva is the author of 'Genetic Diversity Among Jews Diseases and Markers at the DNA Level' with ISBN 9780195068177 and ISBN 0195068173.
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