Calculation of Drug Lipophilicity: The Hydrophobic Fragmental Constant Approach

Comprehensive and comparative, this 2cookbook2 gives the ingredients and recipes for setting up lipophilicity calculations of a great variety of organic molecules. Of particular interest is the extended presentation of the yet unpublished, revised version of the Sigma f-lipophilicity calculation procedure (REKKER-system). Calculation examples of 36 drugs familiarize the user quickly with the calculation method and allow a comparative quality proof. The useful monograph unites the features of a textbook with those of a handbook for academic and industrial scientists. It gives students an exceptionally clear presentation of the subject and helps scientists save time in the laboratory.Rekker, Roelof F. is the author of 'Calculation of Drug Lipophilicity: The Hydrophobic Fragmental Constant Approach' with ISBN 9783527284221 and ISBN 3527284222.